A study of the bidirectional association between hippocampal volume on magnetic resonance imaging and depression in the elderly.

BACKGROUND Hippocampal volume loss on magnetic resonance imaging (MRI) has been reported in patients with depression. It is uncertain whether a small hippocampus renders a person vulnerable to develop depression or whether it is a consequence of depression. In this study, we addressed whether smaller baseline MRI hippocampal volumes increase the risk of… (More)