A study of the adhesive, locomotory and invasive behaviour of Walker 256 carcinosarcoma cells.

@article{Elvin1985ASO,
  title={A study of the adhesive, locomotory and invasive behaviour of Walker 256 carcinosarcoma cells.},
  author={P. Elvin and V Y Wong and Carlton A. W. Evans},
  journal={Experimental cell biology},
  year={1985},
  volume={53 1},
  pages={9-18}
}
We have succeeded in selecting two variant strains of the Walker 256 carcinosarcoma which display markedly different adhesive properties. Both the high (W256A) and the low (W256S) adhesive variants respond chemotactically towards 10(-8) M f-met-leu-phe (FMLP) although there is a significant difference in their locomotory ability. Nevertheless, the fact that the essentially non-adherent W256S cells can migrate in vitro argues against any simple relationship between adhesion and locomotion. We… CONTINUE READING