A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study.

@article{Dennison2009ASO,
  title={A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study.},
  author={Elaine M. Dennison and Holly Emma Syddall and Karen A. Jameson and Avan Aihie Sayer and Tom R. Gaunt and Santiago Rodriguez and I. N. Day and Cyrus Cooper and Mirjam A Lips},
  journal={The Journal of rheumatology},
  year={2009},
  volume={36 7},
  pages={1520-6}
}
OBJECTIVE We sought evidence of association of candidate single nucleotide polymorphisms (SNP) within the growth hormone-insulin-like growth factor 1 (IGF1) axis, largely selected on the basis of functional data available at the time of our study, with adult bone mass. METHODS Four hundred ninety-eight men and 468 women aged 59-71 years were recruited. A… CONTINUE READING