A study of platelet fibronectin immunofluorescence in peripheral vascular disease and diabetes mellitus.

@article{Ejim1989ASO,
  title={A study of platelet fibronectin immunofluorescence in peripheral vascular disease and diabetes mellitus.},
  author={O S Ejim and Mar{\'i}a del Roc{\'i}o Aguilar Barradas and Dimitri P. Mikhailidis and Leonard W Poulter and A Coumar and Paresh Dandona},
  journal={Microcirculation, endothelium, and lymphatics},
  year={1989},
  volume={5 6},
  pages={373-90}
}
Platelets hyperaggregability and hypersecretion fibronectin (Fn) are known to occur in peripheral vascular disease (PVD) and diabetes mellitus (DM) with microangiopathy. To determine whether an increase in platelet membrane bound Fn constitutes to hyperaggregability of platelets, washed platelets from normal subjects and from patients with peripheral vascular disease and patients with diabetes mellitus were examined for the presence of fibronectin (Fn) by means of fluorescein linked antibody to… CONTINUE READING