A study of naturally occurring feline coronavirus infections in kittens

  title={A study of naturally occurring feline coronavirus infections in kittens},
  author={D. D. Addie and Oswald Jarrett},
  journal={Veterinary Record},
  pages={133 - 137}
Feline coronavirus is a common infection in cats, as indicated by the high prevalence of antibodies against the virus, especially in multicat households. Approximately 5 to 12 per cent of seropositive cats develop classical feline infectious peritonitis. A survey of kittens born into households of seropositive cats demonstrated the existence of healthy coronavirus carriers. Seronegative animals did not appear to excrete virus. No specific antibody titre could be linked to carrier status and… 

Pathogenic characteristics of persistent feline enteric coronavirus infection in cats

The patterns of clinical symptoms, faecal virus shedding and seroconversion were monitored for up to 10 weeks revealing subtle but reproducible differences between the two viruses, the avirulent serotype I viruses.

Phylogenetic Analysis of Feline Coronavirus Strains in an Epizootic Outbreak of Feline Infectious Peritonitis

Phylogenetic analysis showed that the FIP‐associated strains of FCoV from the outbreak were very closely related to the fecally derived strains of feline coronavirus from contemporary‐asymptomatic cats.

Genotyping coronaviruses associated with feline infectious peritonitis

The results support previous studies that implicate S protein mutations in the pathogenesis of FIP and identify deletions in the 3c protein ORF of genomes from two of the FIP samples.


It is now known that healthy FCoV infected cats can have systemic F coV infection, albeit with lower F CoV viral loads than cats with FIP.

Persistence and Evolution of Feline Coronavirus in a Closed Cat-Breeding Colony☆

The combined data support a model in which the endemic infection is maintained by chronically infected carriers, and provide the first formal evidence that FCoV causes chronic enteric infections.

Correlation of Feline Coronavirus Shedding in Feces with Coronavirus Antibody Titer

The results indicate that antibody measurement cannot replace fecal RT-qPCR in the management of FCoV infections in multi-cat environments, but the cats’ antibody titers correlate with the likelihood and frequency of F coV shedding and fecal virus load.

Coronavirus Infection in Cats

  • J. Hoskins
  • Medicine, Biology
    Veterinary Clinics of North America: Small Animal Practice
  • 1993