A study of gut immunity to enteral endotoxin in rats of different ages: a possible cause for necrotizing enterocolitis.

@article{Chan2002ASO,
  title={A study of gut immunity to enteral endotoxin in rats of different ages: a possible cause for necrotizing enterocolitis.},
  author={K. L. Chan and Jason Yen-Ping Ho and Kwok Wah Chan and Paul Kwong-hang Tam},
  journal={Journal of pediatric surgery},
  year={2002},
  volume={37 10},
  pages={1435-40}
}
PURPOSE Immature gut immunity can be a predisposing factor for necrotizing enterocolitis (NEC). The gut active immunity and innate defense to the Escherichia coli endotoxin lipopolysaccharide (LPS) in immature and mature rats were studied. METHODS LPS, started at a dose of 10 mg/kg, was instilled into the stomachs of fetal, newborn, 1-month and 3-month-old rats. Boost doses and normal saline control instillations were given on day 14. Rats that died after instillation had detailed postmortem… CONTINUE READING
10 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…