A study of chromosome 11p13 translocations involving TCR beta and TCR delta in human T cell leukaemia.

Abstract

A frequent site of translocation damage in human T-ALL has been localized to a specific region of chromosome band 11p13. Five new T-ALL cases are described which break in the major T-ALLbcr region of 11p13, two involving a novel translocation t(7;11)(q35;p13), with breakage at the T cell receptor (TCR) beta gene from 7q35, and three involving TCR delta from… (More)

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@article{Garcia1991ASO, title={A study of chromosome 11p13 translocations involving TCR beta and TCR delta in human T cell leukaemia.}, author={I. Garcia and Yoshio Kaneko and Rogelio Gonz{\'a}lez-Sarmiento and K. Campbell and L. White and Tobias Konrad Boehm and Terence H. Rabbitts}, journal={Oncogene}, year={1991}, volume={6 4}, pages={577-82} }