A structure-based model of arterial remodeling in response to sustained hypertension.

@article{Tsamis2009ASM,
  title={A structure-based model of arterial remodeling in response to sustained hypertension.},
  author={Alkiviadis Tsamis and Nikos Stergiopulos and Alexander Rachev},
  journal={Journal of biomechanical engineering},
  year={2009},
  volume={131 10},
  pages={101004}
}
A novel structure-based mathematical model of arterial remodeling in response to a sustained increase in pressure is proposed. The model includes two major aspects of remodeling in a healthy matured vessel. First, the deviation of the wall stress and flow-induced shear stress from their normal physiological values drives the changes in the arterial geometry. Second, the new mass that is produced during remodeling results from an increase in the mass of smooth muscle cells and collagen fibers… CONTINUE READING

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