A structural perspective on ClC channel and transporter function.

@article{Dutzler2007ASP,
  title={A structural perspective on ClC channel and transporter function.},
  author={Raimund Dutzler},
  journal={FEBS letters},
  year={2007},
  volume={581 15},
  pages={2839-44}
}
The ClC chloride channels and transporters constitute a large family of membrane proteins that is involved in a variety of physiological processes. All members share a conserved molecular architecture that consists of a complex transmembrane transport domain followed by a cytoplasmic domain. Despite the strong conservation, the family shows an unusually… CONTINUE READING