A structural concept for nucleoli of Dictyostelium discoideum deduced from dissociation studies


We aimed to establish whether there is a matrix structure in the nucleolus to which the ribosomal DNA (rDNA) is strongly attached. To detect artifacts that might occur during the harsh histone extraction procedures frequently used for matrix preparation, we dissociated nucleoli of Dictyostelium discoideum with a range of NaCl or heparin concentrations. With… (More)
DOI: 10.1007/BF00292894


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