A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis.

@article{Adams2002ASF,
  title={A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis.},
  author={Jerry L. Adams and Pearl Huang and Denis Patrick},
  journal={Current opinion in chemical biology},
  year={2002},
  volume={6 4},
  pages={486-92}
}
Tumour growth is dependent on multiple factors, including the physiological process of angiogenesis. Several opportunities for inhibiting angiogenesis with targeted therapies have been identified and are currently being evaluated for clinical efficacy. Some of the most promising approaches include small-molecule inhibitors for the tyrosine receptor kinase… CONTINUE READING