A strategy for the contrast enhancement of malignant tumors using dynamic computed tomography and intravascular pharmacokinetics.


Sequential dynamic computed tomographic (CT) body scans were performed during administration of diatrizoate (intravascular bolus and infusion) in 18 cancer patients, three patients with cysts, and four rabbits with V2 carcinoma. The best diagnostic images occurred soon after the bolus was given (within 60--90 sec.). Tumors and normal tissue became isodense… (More)


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