A stop-codon mutation in the BRI gene associated with familial British dementia.

Abstract

Familial British dementia (FBD), previously designated familial cerebral amyloid angiopathy-British type, is an autosomal dominant disorder of undetermined origin characterized by progressive dementia, spasticity, and cerebellar ataxia, with onset at around the fifth decade of life. Cerebral amyloid angiopathy, non-neuritic and perivascular plaques and… (More)

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Cite this paper

@article{Vidal1999ASM, title={A stop-codon mutation in the BRI gene associated with familial British dementia.}, author={Ruben Vidal and Blas Frangione and Agueda A Rostagno and Simon Mead and T. Revesz and Gordon Plant and Jorge A. Ghiso}, journal={Nature}, year={1999}, volume={399 6738}, pages={776-81} }