A stereoselective synthesis of α-isosparteine

  title={A stereoselective synthesis of $\alpha$-isosparteine},
  author={Hitoshi Oinuma and Shigeyuki Dan and Hiroshi Kakisawa},
  journal={Journal of The Chemical Society, Chemical Communications},
Successive cycloaddition of Δ1-piperidiene 1-oxide to 4H-pyran proceeded regio- and stereo-selectively to afford a 2:1 adduct, catalytic hydrogenation of which gave α-isosparteine in high yield. 
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Published data on the synthesis and transformations of 2,3,4,5-tetrahydropyridine 1-oxides are summarized for the first time, classified, and analyzed.
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