A stem-loop "kissing" model for the initiation of recombination and the origin of introns.

@article{Forsdyke1995AS,
  title={A stem-loop "kissing" model for the initiation of recombination and the origin of introns.},
  author={Donald R. Forsdyke},
  journal={Molecular biology and evolution},
  year={1995},
  volume={12 5},
  pages={949-58}
}
Mutations which improve the efficiency of recombination should affect either the proteins which mediate recombination or their substrate, DNA itself. The former mutations would be localized to a few sites. The latter would be dispersed. Studies of hybridization between RNA molecules have suggested that recombination may be initiated by a homology search involving the "kissing" of the tips of stem loops. This predicts that, in the absence of other constraints, mutations which assist the… CONTINUE READING

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Conservation of stem - loop potential in introns of snake venom phospholipase A 2 genes : an application of FORSD analysis

  • D. R. FORSDYKE
  • Adv . Mutagenesis Res .

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