A statistical model for dissecting genomic imprinting through genetic mapping

@article{Cui2006ASM,
  title={A statistical model for dissecting genomic imprinting through genetic mapping},
  author={Yuehua Cui and James M. Cheverud and Rongling Wu},
  journal={Genetica},
  year={2006},
  volume={130},
  pages={227-239}
}
As a result of nonequivalent genetic contribution of maternal and paternal genomes to offsprings, genomic imprinting or called parent-of-origin effect, has been broadly identified in plants, animals and humans. Its role in shaping organism’s development has been unanimously recognized. However, statistical methods for identifying imprinted quantitative trait loci (iQTL) and estimating the imprinted effect have not been well developed. In this article, we propose an efficient statistical… CONTINUE READING
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