A spoonful of sugar makes the melanoma go: the role of heparan sulfate proteoglycans in melanoma metastasis.

Abstract

Heparan sulfate proteoglycans (HSPGs) have been shown to regulate signaling in many systems and are of increasing interest in cancer. While these are not the only sugars to drive melanoma metastasis, HSPGs play important roles in driving metastatic signaling cascades in melanoma. The ability of these proteins to modulate ligand-receptor interactions in… (More)
DOI: 10.1111/j.1755-148X.2011.00918.x

Cite this paper

@article{OConnell2011ASO, title={A spoonful of sugar makes the melanoma go: the role of heparan sulfate proteoglycans in melanoma metastasis.}, author={M P O'Connell and Ashani T Weeraratna}, journal={Pigment cell & melanoma research}, year={2011}, volume={24 6}, pages={1133-47} }