A spontaneous estrogen dependent, tamoxifen sensitive mouse mammary tumor: a new model system to study hormone-responsiveness in immune competent mice

@article{Simian2007ASE,
  title={A spontaneous estrogen dependent, tamoxifen sensitive mouse mammary tumor: a new model system to study hormone-responsiveness in immune competent mice},
  author={Marina Simian and Teresita D Manzur and Vanina Rodr{\'i}guez and Elisa Dora Bal de Kier Joff{\'e} and Slobodanka A Klein},
  journal={Breast Cancer Research and Treatment},
  year={2007},
  volume={113},
  pages={1-8}
}
Currently, an in vivo spontaneous model of estrogen dependent, tamoxifen sensitive breast cancer does not exist. We show here the characterization of the M05 mammary tumor that appeared spontaneously in a 1-year-old virgin female BALB/c mouse in our animal facility. The M05 tumor is a semi-differentiated adenocarcinoma that expresses estrogen and… CONTINUE READING