A splice variant of E2-2 basic helix-loop-helix protein represses the brain-specific fibroblast growth factor 1 promoter through the binding to an imperfect E-box.

Abstract

We previously demonstrated that a cis-element (-489 to -467) in the brain-specific fibroblast growth factor (FGF)-1 promoter (FGF-1.B) binds multiple nuclear factors, and this binding enhances transcriptional activity of this promoter. Here we report the isolation of three cDNA clones, VL1, VL2 and VL3, from a human brain stem cDNA expression library using… (More)

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@article{Liu1998ASV, title={A splice variant of E2-2 basic helix-loop-helix protein represses the brain-specific fibroblast growth factor 1 promoter through the binding to an imperfect E-box.}, author={Yunhui Liu and S. K. Ray and X. Q. Yang and Vera Luntz-Leybman and Ilene Chiu}, journal={The Journal of biological chemistry}, year={1998}, volume={273 30}, pages={19269-76} }