A spinal cord surrogate with nanoscale porosity for in vitro simulations of restorative neurosurgical techniques

@inproceedings{Gillies2002ASC,
  title={A spinal cord surrogate with nanoscale porosity for in vitro simulations of restorative neurosurgical techniques},
  author={George T. Gillies and Thomas Wilhelm and Joseph A. C. Humphrey and Helen L Fillmore and Kathryn L. Holloway and William C. Broaddus},
  year={2002}
}
The development of strategies for the regrowth of axons through a section of damaged spinal cord could benefit from the availability of an in vitro model in which the potential clinical utility of candidate techniques could be assessed preliminarily. We have designed a spinal cord surrogate for this purpose; it uses 0.6% agarose gel as the parenchymal component and has a fibrous-like longitudinal structure. At this concentration, the pore size distribution of the homogeneous gel ranges from… CONTINUE READING

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