A spicy family tree: TRPV1 and its thermoceptive and nociceptive lineage.

Abstract

In the current issue, Mishra and colleagues demonstrate that mice lacking somatosensory neurons in the TRPV1 lineage are completely insensitive to thermal stimuli of any quality or modality, including both hot and cold temperatures. TRPV1 is a heat-gated ion channel expressed in most heat-sensitive nociceptive neurons and is the receptor for capsaicin, the… (More)
DOI: 10.1038/emboj.2010.350

Topics

1 Figure or Table

Cite this paper

@article{Mckemy2011ASF, title={A spicy family tree: TRPV1 and its thermoceptive and nociceptive lineage.}, author={D D Mckemy}, journal={The EMBO journal}, year={2011}, volume={30 3}, pages={453-5} }