A spectrophotometric assay for the detection of 2-aminophenols in biological samples.

N. Cnubben; B. Blaauboer; S. Juyn; J. Vervoort; I. Rietjens

DOI:10.1006/ABIO.1994.1314

Corpus ID: 29451027

A spectrophotometric assay for the detection of 2-aminophenols in biological samples.

@article{Cnubben1994ASA,
  title={A spectrophotometric assay for the detection of 2-aminophenols in biological samples.},
  author={N. Cnubben and B. Blaauboer and S. Juyn and J. Vervoort and I. Rietjens},
  journal={Analytical biochemistry},
  year={1994},
  volume={220 1},
  pages={
          165-71
        }
}

N. Cnubben, B. Blaauboer, +2 authors I. Rietjens

Published 1994

Chemistry, Medicine

Analytical biochemistry

A sensitive and efficient spectrophotometric assay is described for the determination of 2-aminophenols in biological samples. Using ferric ions as a metal catalyst, 2-aminophenol dimerizes in an acidic aqueous environment to 2-hydroxyisophenoxazin-3-one, an intensively colored dye. The newly developed assay is suitable for the detection of 2-aminophenols in the micromolar range. The paper demonstrates that this chemical assay is also applicable for the determination of 2-aminophenols… CONTINUE READING

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