A spectrophotometric assay for the detection of 2-aminophenols in biological samples.

@article{Cnubben1994ASA,
  title={A spectrophotometric assay for the detection of 2-aminophenols in biological samples.},
  author={N. Cnubben and B. Blaauboer and S. Juyn and J. Vervoort and I. Rietjens},
  journal={Analytical biochemistry},
  year={1994},
  volume={220 1},
  pages={
          165-71
        }
}
  • N. Cnubben, B. Blaauboer, +2 authors I. Rietjens
  • Published 1994
  • Chemistry, Medicine
  • Analytical biochemistry
  • A sensitive and efficient spectrophotometric assay is described for the determination of 2-aminophenols in biological samples. Using ferric ions as a metal catalyst, 2-aminophenol dimerizes in an acidic aqueous environment to 2-hydroxyisophenoxazin-3-one, an intensively colored dye. The newly developed assay is suitable for the detection of 2-aminophenols in the micromolar range. The paper demonstrates that this chemical assay is also applicable for the determination of 2-aminophenols… CONTINUE READING
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