A specific competitive antagonist of the vascular action of angiotensin. II.

The effect of l-Asn-8-Ak-angiotensin II (Asn-Arg-Val-Tyr-Val-His-Pro-Ala) on the vascular action of angiotensin II was studied with rabbit aortic strips, pithed rats, and conscious rats. Dose-response (contraction) curves for angiotensin II on rabbit aortic strips shifted progressively to the right with increasing bath concentrations of l-Asn-8-Ala… CONTINUE READING