A software tool to generate simulated white matter structures for the assessment of fibre-tracking algorithms

@article{Close2009AST,
  title={A software tool to generate simulated white matter structures for the assessment of fibre-tracking algorithms},
  author={Thomas G. Close and Jacques-Donald Tournier and Fernando Calamante and Leigh A. Johnston and Iven M. Y. Mareels and Alan Connelly},
  journal={NeuroImage},
  year={2009},
  volume={47 4},
  pages={1288-300}
}
The assessment of Diffusion-Weighted MRI (DW-MRI) fibre-tracking algorithms has been limited by the lack of an appropriate 'gold standard'. Practical limitations of alternative methods and physical models have meant that numerical simulations have become the method of choice in practice. However, previous numerical phantoms have consisted of separate fibres embedded in homogeneous backgrounds, which do not capture the true nature of white matter. In this paper we describe a method that is able… CONTINUE READING