A sodium channel point mutation is associated with resistance to DDT and pyrethroid insecticides in the peach-potato aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae).

@article{MartnezTorres1999ASC,
  title={A sodium channel point mutation is associated with resistance to DDT and pyrethroid insecticides in the peach-potato aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae).},
  author={David Mart{\'i}nez-Torres and Stephen Paul Foster and Linda M. Field and Alan L. Devonshire and Martin S. Williamson},
  journal={Insect molecular biology},
  year={1999},
  volume={8 3},
  pages={339-46}
}
The voltage-gated sodium channel is the primary target site of DDT and pyrethroid insecticides, and point mutations in the domain II region of the channel protein have been implicated in the knockdown resistant (kdr ) phenotype of several insect species. Here, we report that one of these mutations, a leucine-to-phenylalanine replacement in transmembrane segment IIS6, is also found in certain insecticide-resistant clones of the peach-potato aphid, Myzus persicae. The mutation was present in four… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

Insect sodium channels and insecticide resistance

Invertebrate Neuroscience • 2006
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…