A small plant with big benefits: Fenugreek (Trigonella foenum‐graecum Linn.) for disease prevention and health promotion

@article{NagulapalliVenkata2017ASP,
  title={A small plant with big benefits: Fenugreek (Trigonella foenum‐graecum Linn.) for disease prevention and health promotion},
  author={Kalyan C. Nagulapalli Venkata and Anand Swaroop and Debasis Bagchi and Anupam Bishayee},
  journal={Molecular Nutrition \& Food Research},
  year={2017},
  volume={61},
  pages={\&NA;}
}
Plant-derived natural products have long-standing utility toward treating degenerative diseases. It is estimated that about two-thirds of world population depend on traditional medicine for primary medical needs. Fenugreek (Trigonella foenum-graecum Linn.), a short-living annual medicinal plant belonging to Fabaceae family, is used extensively in various parts of the world as herb, food, spice, and traditional medicine. Fenugreek is considered as one of the oldest medicinal plants and its… 
View on Wolters Kluwer
ncbi.nlm.nih.gov
94 Citations
Highly Influential Citations
2
Background Citations
22
Methods Citations
2

Figures and Tables from this paper

94 Citations

Citation Type

Citation Type

Advances on application of fenugreek seeds as functional foods: Pharmacology, clinical application, products, patents and market
TLDR
This review highlights the phytochemicals, bioactivity (animal aspects) and clinical application of fenugreek from recent literatures and products, markets and patents from database.
Nutritional and therapeutic properties of fenugreek (Trigonella foenum-graecum): a review
TLDR
The present review is an attempt to highlight the important nutritional benefits and curative applications of fenugreek as an effectual therapeutic agent against different diseases.
Fenugreek in Health and Disease
TLDR
The addition of fenugreek in the drinking water of poultry reduces stress, and this can be an important strategy to replace the use of antibiotics such as enrofloxacin as an anti-stress agent, and thus the issues of antibiotic residues in meat, as well as widely developing antibiotic resistance, would be less.
Study of Bioactive Components Present in Oil Extracted from Fenugreek Seed: Review
A fenugreek seed (Trigonella foenum-graecum) is a native of India, and also found in Mediterranean region, southern Europe, Africa and western Asia. These seeds have their importance due to the…
Active Compounds, Health Effects, and Extraction of Unconventional Plant Seed Oils
TLDR
This chapter summarizes the specialty plant seed oils, their bioactive compounds and functional and nutraceutical properties, as well as the novel extraction methods.
Anti-Inflammatory Subfractions Separated from Acidified Chloroform Fraction of Fenugreek Seeds (Trigonella foenum-graecum L.)
TLDR
The separation of flavonoid-rich fractions with anti-inflammatory effect from fenugreek seeds has succeeded and it is hoped the separated fractions also would be free of gastrointestinal side effects.
Determination of Bioactive Compounds of Fenugreek (Trigonella foenum-graecum) Seeds Using LC-MS Techniques.
TLDR
The analytical method was validated and successfully applied for simultaneous determination of compounds in Fenugreek seeds, which indicated the suitability of the validated method for its quality control.
Novel Anti-Tubulin Compounds from Trigonella foenum-graecum Seeds; Insights into In-vitro and Molecular Docking Studies
TLDR
Although this study has evaluated the anticancer potential of Trigonella foenum-graecum as a promising natural source for new anticancer agents, fenugreek biological activity needs further research and investigations on their mechanism of action and toxicity profile.
PROPRIÉTÉS PHARMACOLOGIQUES DE L’EXTRAIT AQUEUX ET DES HUILES ESSENTIELLES DES GRAINES DE FENUGREC (TRIGONELLA FOENUM-GRAECUM. L.)
Description of the subject: Fenugreek is known as a medicinal plant with multiple therapeutic properties related to its richness in carotenoids, polyphenols, fatty acids, proteins with essential…
Advancement and Future Directions towards Herbal Treatment for Various Diseases
TLDR
Herbal drug for treatment of some diseases found, which contain phytochemicals that have antidiabetic, anticarcinogenic, anti-inflammatory, antibiotic, antioxidant, antimicrobial and antiplatelet effects on the human health.
...
...

References

SHOWING 1-10 OF 209 REFERENCES
Pharmacological effects of Trigonella foenum-graecum L. in health and disease
TLDR
The resarch on Trigonella exhibits its health benefits and potential medicinal properties in various indications and has little or no side effects, suggesting its pharmaceutical, therapeutic and nutritional potential.
Holistic approach of Trigonella foenum-graecum in Phytochemistry and Pharmacology- A Review
India is a country of herbs where a lot of varieties are cultivated, and their formulation developed and used for preventing, mitigating and curing of diseases and other health problems. Trigonella…
Compounds in functional food fenugreek spice exhibit anti-inflammatory and antioxidant activities
Fenugreek (Trigonella foenum-graecum): A Review of Health Beneficial Physiological Effects
TLDR
The antidiabetic and hypocholesterolemic property of fenugreek, both of which are mainly attributable to the intrinsic dietary fiber constituent, have promising nutraceutical value.
A Review on the Functional Properties, Nutritional Content, Medicinal Utilization and Potential Application of Fenugreek
TLDR
Fenugreek (Trigonella foenum-gracum) is one of the most promising medicinal herbs, known from ancient times, having nutritional value too and it is used as food stabilizer, adhesive and emulsifying agent due its fibre, protein and gum content.
Alkaloid and flavonoid rich fractions of fenugreek seeds (Trigonella foenum-graecum L.) with antinociceptive and anti-inflammatory effects.
Chemomodulatory Effect of Trigonella foenum graecum (L.) Seed Extract on Two Stage Mouse Skin Carcinogenesis
TLDR
The TFGS extract treatment was most effective when treated throughout all the stages of tumorigenesis, and showed a modulatory influence on mouse hepatic antioxidant defense system (GSH and LPO level).
Anti-inflammatory and anti-melanogenic steroidal saponin glycosides from Fenugreek (Trigonella foenum-graecum L.) seeds.
TLDR
Results indicate that fenugreek extract and its active constituents could protect against skin damage.
Toxicological properties of fenugreek (Trigonella foenum graecum).
  • M. Ouzir, K. El Bairi, S. Amzazi
  • Biology
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2016
Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line
TLDR
Results indication that pure and impure diosgenin prevents telomerase activity by down regulation of the hTERT gene expression in A549 lung cancer cell line, with the difference that pure compound is more effective than another.
...
...