A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii.

@article{Carey2004ASA,
  title={A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii.},
  author={Kimberly L. Carey and Nicholas James Westwood and Timothy J Mitchison and Gary E. Ward},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 19},
  pages={
          7433-8
        }
}
Toxoplasma gondii is the most common protozoan parasite of humans. Infection with T. gondii can lead to life-threatening disease as a result of repeated cycles of host cell invasion, parasite replication, and host cell lysis. Relatively little is known about the invasive mechanisms of T. gondii and related parasites within the Phylum Apicomplexa (including Plasmodium spp., the causative agents of malaria), due to difficulties associated with studying genes essential to invasion in haploid… CONTINUE READING
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