A small microbial genome: the end of a long symbiotic relationship?

  title={A small microbial genome: the end of a long symbiotic relationship?},
  author={Vicente P{\'e}rez-Brocal and Rosario Gil and Silvia Ramos and Araceli Lamelas and Marina Postigo and Jos{\'e} Manuel Michelena and Francisco Jos{\'e} Fraga Silva and Andr{\'e}s Moya and Amparo Latorre},
  volume={314 5797},
Intracellular bacteria are characterized by genome reduction. The 422,434-base pair genome of Buchnera aphidicola BCc, primary endosymbiont of the aphid Cinara cedri, is approximately 200 kilobases smaller than the previously sequenced B. aphidicola genomes. B. aphidicola BCc has lost most metabolic functions, including the ability to synthesize the essential amino acid tryptophan and riboflavin. In addition, most retained genes are evolving rapidly. Possibly, B. aphidicola BCc is losing its… CONTINUE READING
Highly Influential
This paper has highly influenced 18 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS