A small-conductance charybdotoxin-sensitive, apamin-resistant Ca2+-activated K+ channel in aortic smooth muscle cells (A7r5 line and primary culture)

@article{Renterghem1992ASC,
  title={A small-conductance charybdotoxin-sensitive, apamin-resistant Ca2+-activated K+ channel in aortic smooth muscle cells (A7r5 line and primary culture)},
  author={Catherine Van Renterghem and Michel Lazdunski},
  journal={Pfl{\"u}gers Archiv},
  year={1992},
  volume={420},
  pages={417-423}
}
A small conductance K+ channel was identified in smooth muscle cells of the rat aortic cell line A7r5 and also in rat aortic smooth muscle cells in primary culture, using conventional single-channel recording techniques. The single-channel conductance shows no rectification, either in the range −70 to +40 mV under asymmetrical conditions (9.1 pS), or in the range −100 to +50 mV in symmetrical 150 mM K+ (37 pS). Channel activity is reversibly inhibited by extracellular application of… CONTINUE READING
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A CaZ+-activated K + channel from rabbit aorta: modulation by cromakalim

  • CH Gelband, NJ Lodge, C Van Breemen
  • Eur J Pharmacol
  • 1989

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