A small RNA response at DNA ends in Drosophila

@inproceedings{Michalik2012ASR,
  title={A small RNA response at DNA ends in Drosophila},
  author={Katharina M. Michalik and Romy B{\"o}ttcher and Klaus F{\"o}rstemann},
  booktitle={Nucleic acids research},
  year={2012}
}
  • Katharina M. Michalik, Romy Böttcher, Klaus Förstemann
  • Published in Nucleic acids research 2012
  • Biology, Medicine
  • Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently reported double-strand break (DSB)-induced RNAs or Dicer- and Drosha-dependent small RNAs in Arabidopsis and vertebrates. Active transcription in the vicinity of the break amplifies this small RNA response, demonstrating that the normal messenger… CONTINUE READING

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