A single-step isolation by centrifugal partition chromatography of the potential anti-inflammatory glaucolide B from Lepidaploa chamissonis.

  title={A single-step isolation by centrifugal partition chromatography of the potential anti-inflammatory glaucolide B from Lepidaploa chamissonis.},
  author={Layzon Antonio Lemos da Silva and Louis Pergaud Sandjo and Eduarda Fratoni and Yeo Jim Kinoshita Moon and Eduardo Monguilhott Dalmarco and Maique Weber Biavatti},
  journal={Journal of chromatography. A},
Sesquiterpene lactones (SL) are commonly found in Asteraceae and present a promising anti-inflammatory activity. Previously described in Lepidaploa genus, glaucolide B has never been investigated for its anti-inflammatory potential. This study aimed to establish an efficient process for the extraction of glaucolide B (1) from Lepidaploa chamissonis leaves and to develop a simple and fast method for its purification by using centrifugal partition chromatography (CPC), as well as to investigate… 
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