A single rep protein initiates replication of multiple genome components of faba bean necrotic yellows virus, a single-stranded DNA virus of plants.

@article{Timchenko1999ASR,
  title={A single rep protein initiates replication of multiple genome components of faba bean necrotic yellows virus, a single-stranded DNA virus of plants.},
  author={Tatiana Timchenko and F de Kouchkovsky and Lina Katul and Chella David and Heinrich Josef Vetten and Bruno Gronenborn},
  journal={Journal of virology},
  year={1999},
  volume={73 12},
  pages={10173-82}
}
Faba bean necrotic yellows virus (FBNYV) belongs to the nanoviruses, plant viruses whose genome consists of multiple circular single-stranded DNA components. Eleven distinct DNAs, 5 of which encode different replication initiator (Rep) proteins, have been identified in two FBNYV isolates. Origin-specific DNA cleavage and nucleotidyl transfer activities were shown for Rep1 and Rep2 proteins in vitro, and their essential tyrosine residues that catalyze these reactions were identified by site… CONTINUE READING