A single positively selected West Nile viral mutation confers increased virogenesis in American crows

@article{Brault2007ASP,
  title={A single positively selected West Nile viral mutation confers increased virogenesis in American crows},
  author={Aaron C Brault and Claire Y-H Huang and Stanley Langevin and Richard M. Kinney and Richard A. Bowen and Wanichaya N. Ramey and Nicholas A. Panella and Edward C. Holmes and Ann M Powers and Barry R. Miller},
  journal={Nature Genetics},
  year={2007},
  volume={39},
  pages={1162-1166}
}
West Nile virus (WNV), first recognized in North America in 1999, has been responsible for the largest arboviral epiornitic and epidemic of human encephalitis in recorded history. Despite the well-described epidemiological patterns of WNV in North America, the basis for the emergence of WNV-associated avian pathology, particularly in the American crow (AMCR) sentinel species, and the large scale of the North American epidemic and epiornitic is uncertain. We report here that the introduction of… CONTINUE READING

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