A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair.

Abstract

BACKGROUND Recombinant human bone morphogenetic protein-2 (rhBMP-2), surgically implanted with a matrix material, has been shown to induce bone formation and enhance fracture repair. The purpose of this investigation was to test the hypothesis that a single, local, percutaneous injection of rhBMP-2 would accelerate fracture-healing in a standard rat femoral… (More)

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