A single molecule immunoassay by localized surface plasmon resonance.

Noble metal nanoparticles exhibit sharp spectral extinction peaks at visible and near-infrared frequencies due to the resonant excitation of their free electrons, termed localized surface plasmon resonance (LSPR). Since the resonant frequency is dependent on the refractive index of the nanoparticle surroundings, LSPR can be the basis for sensing molecular… CONTINUE READING