A single-molecule approach to explore binding, uptake and transport of cancer cell targeting nanotubes.

@article{Lamprecht2014ASA,
  title={A single-molecule approach to explore binding, uptake and transport of cancer cell targeting nanotubes.},
  author={Constanze Lamprecht and Birgit Plochberger and Verena Ruprecht and Stefan Wieser and Christian Rankl and Elena Heister and Barbara Unterauer and Mario Brameshuber and J{\"u}rgen Danzberger and Petar Lukanov and Emmanuel Flahaut and Gisela Schuetz and P. Hinterdorfer and Andreas Ebner},
  journal={Nanotechnology},
  year={2014},
  volume={25 12},
  pages={125704}
}
In the past decade carbon nanotubes (CNTs) have been widely studied as a potential drug-delivery system, especially with functionality for cellular targeting. Yet, little is known about the actual process of docking to cell receptors and transport dynamics after internalization. Here we performed single-particle studies of folic acid (FA) mediated CNT… CONTINUE READING