A single histone H1 isoform (H1.1) is essential for chromatin silencing and germline development in Caenorhabditis elegans.

@article{Jedrusik2001ASH,
  title={A single histone H1 isoform (H1.1) is essential for chromatin silencing and germline development in Caenorhabditis elegans.},
  author={Monika A Jedrusik and Ekkehard Schulze},
  journal={Development},
  year={2001},
  volume={128 7},
  pages={1069-80}
}
In remarkable contrast to somatic cells, the germline of the nematode Caenorhabditis elegans efficiently silences transgenic DNA. The molecular mechanisms responsible for this have been shown to implicate chromatin proteins encoded by the mes genes (Kelly, W. G. and Fire, A. (1998) Development 125, 2451-2456), of which two are the C. elegans homologs of Polycomb Group gene transcriptional repressors. We have analyzed the contribution of the histone H1 gene family to this specific aspect of germ… CONTINUE READING

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