A single gene for bovine high molecular weight and low molecular weight kininogens

@article{Kitamura1983ASG,
  title={A single gene for bovine high molecular weight and low molecular weight kininogens},
  author={Naomi Kitamura and Yoshio Takagaki and Sumiko Furuto and Toshihiro Tanaka and Hiroyuki Nawa and Shigetada Nakanishi},
  journal={Nature},
  year={1983},
  volume={305},
  pages={545-549}
}
A potent vasoactive peptide, bradykinin, is liberated from two distinct kininogens designated low molecular weight (LMW) and high molecular weight (HMW) kininogens1. We have recently cloned and sequenced cDNAs for bovine LMW prekininogens and indicated that LMW prekininogens are encoded by two very similar but distinct mRNAs2. This study concerns the structural basis for the relationship between HMW and LMW prekininogen mRNAs by examination of cDNA clones for bovine HMW prekininogens and a… CONTINUE READING
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