A single female-specific piRNA is the primary determiner of sex in the silkworm

@article{Kiuchi2014ASF,
  title={A single female-specific piRNA is the primary determiner of sex in the silkworm},
  author={T. Kiuchi and Hikaru Koga and M. Kawamoto and Keisuke Shoji and Hiroki Sakai and Y. Arai and Genki Ishihara and S. Kawaoka and S. Sugano and T. Shimada and Yutaka Suzuki and Masataka G. Suzuki and S. Katsuma},
  journal={Nature},
  year={2014},
  volume={509},
  pages={633-636}
}
The silkworm Bombyx mori uses a WZ sex determination system that is analogous to the one found in birds and some reptiles. In this system, males have two Z sex chromosomes, whereas females have Z and W sex chromosomes. The silkworm W chromosome has a dominant role in female determination, suggesting the existence of a dominant feminizing gene in this chromosome. However, the W chromosome is almost fully occupied by transposable element sequences, and no functional protein-coding gene has been… Expand
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