A single episode of juvenile status epilepticus reduces the threshold to adult seizures in a stimulus-specific way.

Abstract

We have previously reported that an episode of pentylenetetrazole (PTZ)-induced status epilepticus (SE) in immature rats induces a long-term increase in cholinergic excitation assessed in the adult brain in vitro. In this in vivo work, we tested the responsiveness of adult SE-conditioned rats to pilocarpine and PTZ, two convulsants with different mechanisms… (More)
DOI: 10.1016/j.eplepsyres.2014.08.001

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@article{Kouis2014ASE, title={A single episode of juvenile status epilepticus reduces the threshold to adult seizures in a stimulus-specific way.}, author={Panayiotis Kouis and Apostolos V Mikroulis and Caterina Psarropoulou}, journal={Epilepsy research}, year={2014}, volume={108 9}, pages={1564-71} }