A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles

  title={A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles},
  author={Yuko Kurosawa and S. Nirengi and Toshiyuki Homma and Kazuki Esaki and M. Ohta and J. Clark and T. Hamaoka},
  journal={Scientific Reports},
  • Yuko Kurosawa, S. Nirengi, +4 authors T. Hamaoka
  • Published 2015
  • Medicine
  • Scientific Reports
  • Our aim was to determine the quantitative effects of a single-dose of Nattokinase (NK) administration on coagulation/fibrinolysis parameters comprehensively in healthy male subjects. A double-blind, placebo-controlled cross-over NK intervention study was carried out in 12 healthy young males. Following the baseline blood draw, each subject was randomized to receive either a single-dose of 2,000 FU NK (NSK-SD, Japan Bio Science Laboratory Co., Ltd) or placebo with subsequent cross-over of the… CONTINUE READING
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