A single dose of mirtazapine modulates neural responses to emotional faces in healthy people

  title={A single dose of mirtazapine modulates neural responses to emotional faces in healthy people},
  author={Nancy B. Rawlings and Ray Norbury and Philip J. Cowen and Catherine J. Harmer},
Single-dose administration of selective serotonin and noradrenaline reuptake blockers has been shown to alter emotional processing in both behavioral and fMRI studies in healthy volunteers. Mirtazapine is a clinically established antidepressant with different pharmacological actions from monoamine reuptake inhibitors, involving blockade of noradrenaline α2-adrenoceptors and multiple 5-HT receptor subtypes. The aim of this study was to investigate the effect of a single dose of mirtazapine on… CONTINUE READING


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