A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

  title={A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex},
  author={Suijuan Zhong and Shu Zhang and Xiaoying Fan and Q. Wu and Liying Yan and Ji Dong and Haofeng Zhang and L. Li and L. Sun and N. Pan and X. Xu and F. Tang and J. Zhang and J. Qiao and Xiaoqun Wang},
  • Suijuan Zhong, Shu Zhang, +12 authors Xiaoqun Wang
  • Published 2018
  • Computer Science, Medicine, Biology
  • Nature
  • The mammalian prefrontal cortex comprises a set of highly specialized brain areas containing billions of cells and serves as the centre of the highest-order cognitive functions, such as memory, cognitive ability, decision-making and social behaviour. Although neural circuits are formed in the late stages of human embryonic development and even after birth, diverse classes of functional cells are generated and migrate to the appropriate locations earlier in development. Dysfunction of the… CONTINUE READING
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