A single GATA factor plays discrete, lineage specific roles in ascidian heart development.

Abstract

GATA family transcription factors are core components of the vertebrate heart gene network. GATA factors also contribute to heart formation indirectly through regulation of endoderm morphogenesis. However, the precise impact of GATA factors on vertebrate cardiogenesis is masked by functional redundancy within multiple lineages. Early heart specification in… (More)
DOI: 10.1016/j.ydbio.2011.01.007

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