A simultaneous single breath measurement of pulmonary diffusing capacity with nitric oxide and carbon monoxide.

@article{Borland1989ASS,
  title={A simultaneous single breath measurement of pulmonary diffusing capacity with nitric oxide and carbon monoxide.},
  author={Colin D R Borland and Timothy W. Higenbottam},
  journal={The European respiratory journal},
  year={1989},
  volume={2 1},
  pages={
          56-63
        }
}
Pulmonary diffusing capacity (DL) for carbon monoxide (CO) and nitric oxide (NO) were simultaneously measured in man using the single breath method, by adding 4O ppm of NO to the inspired gas and analysing the expirate for NO by a chemiluminescent method. The mean ratio of DLNO to DLCO in thirteen subjects was 4.3 (SD 0.3), mean DLNO = 49 mmol.min-1.kPa-1 (SD 10) and mean DLCO = 11 mmol.min-1.kPa-1 (SD 2). An increase in alveolar oxygen concentration from a mean of 18 to 68% in five subjects… CONTINUE READING

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