A simulation study of the number of events per variable in logistic regression analysis.

@article{Peduzzi1996ASS,
  title={A simulation study of the number of events per variable in logistic regression analysis.},
  author={Peter Peduzzi and John P Concato and Erica Kemper and Theodore Holford and Alvan R. Feinstein},
  journal={Journal of clinical epidemiology},
  year={1996},
  volume={49 12},
  pages={
          1373-9
        }
}
We performed a Monte Carlo study to evaluate the effect of the number of events per variable (EPV) analyzed in logistic regression analysis. The simulations were based on data from a cardiac trial of 673 patients in which 252 deaths occurred and seven variables were cogent predictors of mortality; the number of events per predictive variable was (252/7 =) 36 for the full sample. For the simulations, at values of EPV = 2, 5, 10, 15, 20, and 25, we randomly generated 500 samples of the 673… CONTINUE READING
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