A simulation study of the effects of cardiac anatomy in ventricular fibrillation.

@article{Xie2004ASS,
  title={A simulation study of the effects of cardiac anatomy in ventricular fibrillation.},
  author={Fagen Xie and Zhilin Qu and Junzhong Yang and Ali Baher and James N. Weiss and Alan Garfinkel},
  journal={The Journal of clinical investigation},
  year={2004},
  volume={113 5},
  pages={686-93}
}
In ventricular fibrillation (VF), the principal cause of sudden cardiac death, waves of electrical excitation break up into turbulent and incoherent fragments. The causes of this breakup have been intensely debated. Breakup can be caused by fixed anatomical properties of the tissue, such as the biventricular geometry and the inherent anisotropy of cardiac conduction. However, wavebreak can also be caused purely by instabilities in wave conduction that arise from ion channel dynamics, which… CONTINUE READING
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