Purpose: To develop a musculo-skeletal dynamic model for simulating hand grasp by means of FES in paretic hand. Methods: The skeletal model, which consisted of humerus, radius, ulna and bones of hand, was developed from CT data of. The muscle model, which had been designed by Hase, was developed about flexor carpi ulnaris, felxor carpi radialis, extensor carpi ulnaris, extensor carpi radialis longus and brevis. These muscles had the physical properties that were different from muscle to muscle. In this study, the properties were obtained from the study written by Gregory et al. We installed the muscle model into the skeletal model on the three-dimensional analysis software “Visual Nastran”. Except the wrist joint, the other joints were fixed in this model. We controlled the model by using the numerical analysis software “MATLAB”. Results: We stimulated the extensors with muscle activator 0.4. We could confirm extension of the wrist. Conclusion: The wrist extension on the model suggested the tenodesis grasp in hemiplegic hand.