A simplified surveillance case definition of AIDS derived from empirical clinical data. The Clinical AIDS Study Group, and the Working Group on AIDS case definition.

@article{Weniger1992ASS,
  title={A simplified surveillance case definition of AIDS derived from empirical clinical data. The Clinical AIDS Study Group, and the Working Group on AIDS case definition.},
  author={Bruce G. Weniger and E P Quinh{\~o}es and Anne B. Sereno and M A de Perez and John W. Krebs and C Ismael and Fernando Samuel Sion and C F Ramos-Filho and Carlos Alberto Morais de S{\'a} and Robert H Byers},
  journal={Journal of acquired immune deficiency syndromes},
  year={1992},
  volume={5 12},
  pages={1212-23}
}
A clinical AIDS case definition is needed for surveillance in countries where the CDC case definition is not practical. To derive such a definition, we compared 110 HIV-seropositive and 135 randomly selected HIV-seronegative adult medical-ward inpatients in Brazil. Multivariate analysis of clinical signs and symptoms and simple diagnoses resulted in a discriminant function with sensitivity of 89% and specificity of 96% in predicting for AIDS. These data were the empirical basis for a clinical… CONTINUE READING

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