A simplified diagnostic test in hypoparathyroidism and pseudohypoparathyroidism type I with synthetic 1–38 fragment of human parathyroid hormone

@article{Kruse1987ASD,
  title={A simplified diagnostic test in hypoparathyroidism and pseudohypoparathyroidism type I with synthetic 1–38 fragment of human parathyroid hormone},
  author={Klaus Kruse and Ute Kracht},
  journal={European Journal of Pediatrics},
  year={1987},
  volume={146},
  pages={373-377}
}
Bovine parathyroid extract of E. Lilly (Indianapolis), which has been used to differentiate pseudohypoparathyroidism (PHP) and hypoparathyroidism (HP) is no longer available. We therefore evaluated the usefulness of the synthetic 1–38 fragment of human parathyroid hormone (1–38 hPTH), the biologically active part of the intact hormone, in a simplified modification of the traditional Ellsworth-Howard test. 1–38 hPTH was slowly injected over 2 min at a dose of 0.5 μg/kg body weight in healthy… CONTINUE READING

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